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New skin patch may help reduce body fat

by December 29, 2017 General

Researchers have developed a new type of skin patch that may reduce body and by turning energy-storing white into energy-burning brown

According to the researchers, brown fats are found in babies and they help to keep the baby warm by burning As humans grow older, the amount of brown lessens and is replaced with visceral white fats.

“What we aim to develop is a painless patch that everyone could use easily, is unobtrusive and yet affordable. Most importantly, our solution aims to use a person’s own body fats to burn more energy, which is a natural process in babies,” said Chen Peng, at (NTU),

The new type of skin patch contains hundreds of micro-needles which are loaded with the drug Beta-3 adrenergic receptor agonist or another drug called thyroid hormone T3 triiodothyronine.

When the patch is pressed into the skin for about two minutes, these micro-needles become embedded in the skin and detach from the patch, which can then be removed.

As the needles degrade, the drug molecules then slowly diffuse to the energy-storing white underneath the skin layer, turning them into

Published in the journal Small Methods, this approach could help to address the worldwide problem without resorting to surgical operations or oral medications.

In a laboratory experiments conducted by the researchers showed that the patch could suppress weight gain in mice that were fed a high diet and reduce their mass by over 30 per cent, over a period of four weeks.

“With the embedded micro-needles in the skin of the mice, the surrounding fats started browning in five days, which helped to increase the expenditure of the mice, leading to a reduction in body gain,” said Xu Chenjie, assistant at NTU.

The treated mice also had significantly lower blood cholesterol and fatty acids levels compared to the untreated mice.



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)